Read Chapters 6, 7, 8 of the textbook (link: https://openstax.org/books/biology/pages/preface)
Topic: “How do drugs work?”
Many drugs, legal or not, work by either stimulating or inhibiting specific metabolic enzymes. As such, products of metabolic reactions can be selectively increased or decreased depending on the drugs mechanism of action in the cell.
In your readings, you learned that statins are a class of drugs used to reduce cholesterol levels. Their mechanism of action is to inhibit the enzyme HMG-CoA reductase. HMG-CoA reductase is the enzyme that synthesizes cholesterol from lipids in the body. By inhibiting this enzyme, the levels of cholesterol synthesized in the body can be reduced.
For this paper:
You will research and present a drug of your choice for this assignment. You are free to choose any drug as long as it works by inhibiting a specific enzyme; e.g., statins. You cannot, however, use statins.
Write a 2-3 page (500 750 words, 12 point font) paper including the following elements. Be sure to compose your work with your own words. Do not copy and paste from any source.
Identify the drug as synthetic or biological/natural and describe the chemical structure.
Describe how the chemical structure of the drug is necessary for function; i.e., the cellular mechanism of action.
Identify the drug as either a competitive or allosteric inhibitor. Describe how this works.
Identify one or more adverse effects of the drug. Explain the effect based on the drugs effect on metabolism.
Use in-text citation and provide source references for at least 3 sources. The textbook can be one source.
Check all content for grammar, spelling and be sure that you have properly cited all resources (in APA format) used.
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